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Protein-glutamine gamma-glutamyltransferase : ウィキペディア英語版
Protein-glutamine gamma-glutamyltransferase

In enzymology, a protein-glutamine gamma-glutamyltransferase () is an enzyme that catalyzes the chemical reaction
:protein glutamine + alkylamine \rightleftharpoons protein N5-alkylglutamine + NH3
Thus, the two substrates of this enzyme are protein glutamine and alkylamine, whereas its two products are protein N(5)-alkylglutamine and NH3.
This enzyme participates in complement and coagulation cascades and Huntington's disease. It employs one cofactor, calcium.
== Nomenclature ==

This enzyme belongs to the family of transferases, specifically the aminoacyltransferases. The systematic name of this enzyme class is protein-glutamine:amine gamma-glutamyltransferase. Other names in common use include:
* factor XIIIa,
* fibrin stabilizing factor,
* fibrinoligase,
* glutaminylpeptide gamma-glutamyltransferase,
* polyamine transglutaminase,
* R-glutaminyl-peptide:amine gamma-glutamyl transferase
* tissue transglutaminase, and
* transglutaminase.


抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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